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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
42.73
Human Site:
S469
Identified Species:
58.75
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
S469
E
A
Q
L
L
S
L
S
K
E
K
A
L
L
E
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
S469
E
A
Q
L
L
S
L
S
K
E
K
A
L
L
E
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
S468
E
A
Q
L
L
S
L
S
K
E
K
A
L
L
E
Dog
Lupus familis
XP_533766
1089
122761
S466
E
A
Q
L
L
S
L
S
K
E
K
A
L
L
E
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
S467
E
T
Q
L
L
S
L
S
K
E
K
A
L
L
E
Rat
Rattus norvegicus
NP_446123
1093
121882
S469
E
T
Q
L
L
S
L
S
K
E
K
A
L
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
S476
E
T
Q
L
L
A
V
S
K
E
K
A
F
L
E
Chicken
Gallus gallus
O42184
1433
161009
S584
E
I
K
T
L
S
A
S
N
E
R
M
G
K
E
Frog
Xenopus laevis
Q5PQ23
649
75475
L134
M
G
T
L
K
H
E
L
E
L
Q
K
R
E
K
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
S504
E
S
Q
L
L
A
V
S
K
D
K
A
R
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
S417
E
M
I
A
A
L
Q
S
E
G
E
K
L
S
K
Honey Bee
Apis mellifera
XP_394037
1326
150590
T512
D
L
N
L
D
S
L
T
E
K
H
N
L
H
L
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
S1103
E
S
E
L
H
S
V
S
S
R
L
E
D
E
Q
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
S545
E
S
Q
I
I
H
L
S
Q
Q
N
G
E
L
Q
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
A460
E
I
I
N
Q
V
M
A
E
G
E
E
L
S
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
K441
A
A
A
L
L
K
E
K
D
E
I
I
N
Q
V
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
I192
E
L
R
Q
S
N
Q
I
K
A
L
R
T
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
73.3
40
6.6
66.6
N.A.
20
26.6
26.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
53.3
26.6
93.3
N.A.
40
53.3
53.3
73.3
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
13.3
N.A.
N.A.
26.6
13.3
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
30
6
6
6
12
6
6
0
6
0
48
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
0
6
0
0
0
6
6
0
0
6
0
0
% D
% Glu:
83
0
6
0
0
0
12
0
24
53
12
12
6
12
53
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% F
% Gly:
0
6
0
0
0
0
0
0
0
12
0
6
6
0
0
% G
% His:
0
0
0
0
6
12
0
0
0
0
6
0
0
6
0
% H
% Ile:
0
12
12
6
6
0
0
6
0
0
6
6
0
0
0
% I
% Lys:
0
0
6
0
6
6
0
6
53
6
48
12
0
12
18
% K
% Leu:
0
12
0
71
59
6
48
6
0
6
12
0
53
53
6
% L
% Met:
6
6
0
0
0
0
6
0
0
0
0
6
0
0
0
% M
% Asn:
0
0
6
6
0
6
0
0
6
0
6
6
6
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
53
6
6
0
12
0
6
6
6
0
0
6
12
% Q
% Arg:
0
0
6
0
0
0
0
0
0
6
6
6
12
0
0
% R
% Ser:
0
18
0
0
6
53
0
71
6
0
0
0
0
12
0
% S
% Thr:
0
18
6
6
0
0
0
6
0
0
0
0
6
0
0
% T
% Val:
0
0
0
0
0
6
18
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _